Phagocytosis by stroma confounds coculture studies

Phagocytosis by stroma confounds coculture studies

Summary: Signals provided by the microenvironment can modify and circumvent pathway activities that are therapeutically targeted by drugs. Bone marrow stromal cell coculture models are frequently used to study the influence of the bone marrow niche on ex vivo drug response. Here, we show that mesenc...

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Bibliographic Details
Main Authors: Sophie A. Herbst, Marta Stolarczyk, Tina Becirovic, Felix Czernilofsky, Yi Liu, Carolin Kolb, Mareike Knoll, Marco Herling, Carsten Müller-Tidow, Sascha Dietrich
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:iScience
Subjects:
Biological Sciences
Cell Biology
Stem Cells Research
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221010300

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http://www.sciencedirect.com/science/article/pii/S2589004221010300

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