Complementary Use of Carbohydrate Antigens Lewis a, Lewis b, and Sialyl-Lewis a (CA19.9 Epitope) in Gastrointestinal Cancers: Biological Rationale Towards A Personalized Clinical Application

Complementary Use of Carbohydrate Antigens Lewis a, Lewis b, and Sialyl-Lewis a (CA19.9 Epitope) in Gastrointestinal Cancers: Biological Rationale Towards A Personalized Clinical Application

Carbohydrate antigen 19.9 (CA19.9) is used as a tumor marker for clinical and research purposes assuming that it is abundantly produced by gastrointestinal cancer cells due to a cancer-associated aberrant glycosylation favoring its synthesis. Recent data has instead suggested a different picture, wh...

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Bibliographic Details
Main Authors: Rossella Indellicato, Aida Zulueta, Anna Caretti, Marco Trinchera
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
tumor marker
glycosyltransferase
pancreatic ductal adenocarcinoma
colorectal cancer
selectin ligand
Online Access:https://www.mdpi.com/2072-6694/12/6/1509

Internet

https://www.mdpi.com/2072-6694/12/6/1509

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