Global Transcriptome Analysis Identifies a Diagnostic Signature for Early Disseminated Lyme Disease and Its Resolution

Global Transcriptome Analysis Identifies a Diagnostic Signature for Early Disseminated Lyme Disease and Its Resolution

Lyme disease (LD), caused by Borrelia burgdorferi, is the most common tick-borne infectious disease in the United States. We examined gene expression patterns in the blood of individuals with early disseminated LD at the time of diagnosis (acute) and also at approximately 1 month and 6 months follow...

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Bibliographic Details
Main Authors: Mary M. Petzke, Konstantin Volyanskyy, Yong Mao, Byron Arevalo, Raphael Zohn, Johanna Quituisaca, Gary P. Wormser, Nevenka Dimitrova, Ira Schwartz
Format: Article
Language:English
Published: American Society for Microbiology 2020-03-01
Series:mBio
Subjects:
borrelia burgdorferi
lyme disease
diagnostics
random forest
transcriptome
Online Access:https://doi.org/10.1128/mBio.00047-20

Internet

https://doi.org/10.1128/mBio.00047-20

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