Extracellular vesicles in human semen modulate antigen-presenting cell function and decrease downstream antiviral T cell responses.

Extracellular vesicles in human semen modulate antigen-presenting cell function and decrease downstream antiviral T cell responses.

Human semen contains trillions of extracellular vesicles (SEV) similar in size to sexually transmitted viruses and loaded with potentially bioactive miRNAs, proteins and lipids. SEV were shown to inhibit HIV and Zika virus infectivity, but whether SEV are able also to affect subsequent immune respon...

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Bibliographic Details
Main Authors: Lucia Vojtech, Mengying Zhang, Veronica Davé, Claire Levy, Sean M Hughes, Ruofan Wang, Fernanda Calienes, Martin Prlic, Elizabeth Nance, Florian Hladik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0223901

Internet

https://doi.org/10.1371/journal.pone.0223901

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