Integrative Analyses of Uterine Transcriptome and MicroRNAome Reveal Compromised LIF-STAT3 Signaling and Progesterone Response in the Endometrium of Patients with Recurrent/Repeated Implantation Failure (RIF).

Integrative Analyses of Uterine Transcriptome and MicroRNAome Reveal Compromised LIF-STAT3 Signaling and Progesterone Response in the Endometrium of Patients with Recurrent/Repeated Implantation Failure (RIF).

Intimate two-way interactions between the implantation-competent blastocyst and receptive uterus are prerequisite for successful embryo implantation. In humans, recurrent/repeated implantation failure (RIF) may occur due to altered uterine receptivity with aberrant gene expression in the endometrium...

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Main Authors: Youngsok Choi, Hye-Ryun Kim, Eun Jin Lim, Miseon Park, Jung Ah Yoon, Yeon Sun Kim, Eun-Kyung Kim, Ji-Eun Shin, Ji Hyang Kim, Hwang Kwon, Haengseok Song, Dong-Hee Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4909214?pdf=render

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http://europepmc.org/articles/PMC4909214?pdf=render

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