P2Y2 receptor deficiency aggravates chronic kidney disease progression

P2Y2 receptor deficiency aggravates chronic kidney disease progression

Purinergic signaling is involved in a variety of physiological states. P2 receptors are mainly activated by adenosine triphosphate (ATP). Activation of specific P2Y receptor subtypes might influence progression of kidney disease. To investigate the in vivo effect of a particular P2 receptor subtype...

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Bibliographic Details
Main Authors: Sebastian Alexander Potthoff, Johannes eStegbauer, Jan eBecker, P. Johannes Wagenhaeuser, Blanka eDuvnjak, Lars Christian Rump, Oliver eVonend
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Physiology
Subjects:
ATP
chronic kidney diseases
purinercic receptors
P2Y2 receptor
subtotal nephrectomy
chronic renal failure
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00234/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00234/full

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