Computational identification and experimental validation of microRNAs binding to the Alzheimer-related gene ADAM10

<p>Abstract</p> <p>Background</p> <p>MicroRNAs (miRNAs) are post-transcriptional regulators involved in numerous biological processes including the pathogenesis of Alzheimer’s disease (AD). A key gene of AD, <it>ADAM10</it>, controls the proteolytic processi...

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Bibliographic Details
Main Authors: Augustin Regina, Endres Kristina, Reinhardt Sven, Kuhn Peer-Hendrik, Lichtenthaler Stefan F, Hansen Jens, Wurst Wolfgang, Trümbach Dietrich
Format: Article
Language:English
Published: BMC 2012-05-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/13/35