Increasing the Biological Stability Profile of a New Chemical Entity, UPEI-104, and Potential Use as a Neuroprotectant Against Reperfusion-Injury

Previous work in our laboratory demonstrated the utility of synthetic combinations of two naturally occurring, biologically active compounds. In particular, we combined two known anti-oxidant compounds, lipoic acid and apocynin, covalently linked via an ester bond (named UPEI-100). In an animal mod...

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Bibliographic Details
Main Authors: Tarek M. Saleh, Barry J. Connell, Inan Kucukkaya, Alaa S. Abd-El-Aziz
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Brain Sciences
Subjects:
Online Access:http://www.mdpi.com/2076-3425/5/2/130