Profiling of Epigenetic Features in Clinical Samples Reveals Novel Widespread Changes in Cancer
Aberrations in histone post-translational modifications (PTMs), as well as in the histone modifying enzymes (HMEs) that catalyze their deposition and removal, have been reported in many tumors and many epigenetic inhibitors are currently under investigation for cancer treatment. Therefore, profiling...
Main Authors: | Roberta Noberini, Camilla Restellini, Evelyn Oliva Savoia, Francesco Raimondi, Lavinia Ghiani, Maria Giovanna Jodice, Giovanni Bertalot, Giuseppina Bonizzi, Maria Capra, Fausto Antonio Maffini, Marta Tagliabue, Mohssen Ansarin, Michela Lupia, Marco Giordano, Daniela Osti, Giuliana Pelicci, Susanna Chiocca, Tiziana Bonaldi |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-05-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/11/5/723 |
Similar Items
-
Label-Free Mass Spectrometry-Based Quantification of Linker Histone H1 Variants in Clinical Samples
by: Roberta Noberini, et al.
Published: (2020-10-01) -
PAT-H-MS coupled with laser microdissection to study histone post-translational modifications in selected cell populations from pathology samples
by: Roberta Noberini, et al.
Published: (2017-07-01) -
Mass-spectrometry analysis of histone post-translational modifications in pathology tissue using the PAT-H-MS approach
by: Roberta Noberini, et al.
Published: (2016-06-01) -
Systematic genetics and single‐cell imaging reveal widespread morphological pleiotropy and cell‐to‐cell variability
by: Mojca Mattiazzi Usaj, et al.
Published: (2020-02-01) -
Desmoplastic Small Round Cell Tumour in a Young Woman with Widespread Metastasis and Peritoneal Caking
by: Vidya Monappa, et al.
Published: (2013-12-01)