Profiling of Epigenetic Features in Clinical Samples Reveals Novel Widespread Changes in Cancer

Profiling of Epigenetic Features in Clinical Samples Reveals Novel Widespread Changes in Cancer

Aberrations in histone post-translational modifications (PTMs), as well as in the histone modifying enzymes (HMEs) that catalyze their deposition and removal, have been reported in many tumors and many epigenetic inhibitors are currently under investigation for cancer treatment. Therefore, profiling...

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Bibliographic Details
Main Authors: Roberta Noberini, Camilla Restellini, Evelyn Oliva Savoia, Francesco Raimondi, Lavinia Ghiani, Maria Giovanna Jodice, Giovanni Bertalot, Giuseppina Bonizzi, Maria Capra, Fausto Antonio Maffini, Marta Tagliabue, Mohssen Ansarin, Michela Lupia, Marco Giordano, Daniela Osti, Giuliana Pelicci, Susanna Chiocca, Tiziana Bonaldi
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cancers
Subjects:
epigenetics
histone post-translational modifications
mass spectrometry
proteomics
cancer
cell cycle
cell culture
Online Access:https://www.mdpi.com/2072-6694/11/5/723

Internet

https://www.mdpi.com/2072-6694/11/5/723

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