Anti-folate drug resistance in Africa: meta-analysis of reported dihydrofolate reductase (<it>dhfr</it>) and dihydropteroate synthase (<it>dhps</it>) mutant genotype frequencies in African <it>Plasmodium falciparum </it>parasite populations

<p>Abstract</p> <p>Background</p> <p>Mutations in the dihydrofolate reductase (<it>dhfr</it>) and dihydropteroate synthase (<it>dhps</it>) genes of <it>Plasmodium falciparum </it>are associated with resistance to anti-folate drugs, mo...

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Bibliographic Details
Main Authors: Sridaran Sankar, McClintock Shannon K, Syphard Luke M, Herman Karen M, Barnwell John W, Udhayakumar Venkatachalam
Format: Article
Language:English
Published: BMC 2010-08-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/9/1/247