Inhibition of PP2A activity by H2O2 during mitosis disrupts nuclear envelope reassembly and alters nuclear shape

Cancer: the importance of staying in shape A class of harmful chemical compounds produces morphological abnormalities in the nucleus that may help promote tumor growth. Reactive oxygen species (ROS) are DNA- and protein-damaging molecules that originate both from environmental contaminants and as a...

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Bibliographic Details
Main Authors: Ju-Hyun Ahn, Min-Guk Cho, Seonghyang Sohn, Jae-Ho Lee
Format: Article
Language:English
Published: Nature Publishing Group 2019-06-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-019-0260-0