A Combined Optogenetic-Knockdown Strategy Reveals a Major Role of Tomosyn in Mossy Fiber Synaptic Plasticity
Neurotransmitter release probability (Pr) largely determines the dynamic properties of synapses. While much is known about the role of presynaptic proteins in transmitter release, their specific contribution to synaptic plasticity is unclear. One such protein, tomosyn, is believed to reduce Pr by in...
Main Authors: | Yoav Ben-Simon, Alma Rodenas-Ruano, Karina Alviña, Alice D. Lam, Edward L. Stuenkel, Pablo E. Castillo, Uri Ashery |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-07-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221112471500649X |
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