Group V Secretory Phospholipase A2 Is Involved in Tubular Integrity and Sodium Handling in the Kidney.

Group V (GV) phospholipase A2 (PLA2) is a member of the family of secreted PLA2 (sPLA2) enzymes. This enzyme has been identified in several organs, including the kidney. However, the physiologic role of GV sPLA2 in the maintenance of renal function remains unclear. We used mice lacking the gene enco...

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Main Authors: João Luiz Silva-Filho, Diogo Barros Peruchetti, Felipe Moraes-Santos, Sharon Schilling Landgraf, Leandro Souza Silva, Gabriela Modenesi Sirtoli, Daniel Zamith-Miranda, Christina Maeda Takiya, Ana Acacia Sá Pinheiro, Bruno Lourenço Diaz, Celso Caruso-Neves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4731149?pdf=render