BIASED AGONISM OF THREE DIFFERENT CANNABINOID RECEPTOR AGONISTS IN MOUSE BRAIN CORTEX

Cannabinoid receptors are able to couple to different families of G-proteins when activated by an agonist drug. It has been suggested that different intracellular responses may be activated depending on the ligand. The goal of the present study was to characterize the pattern of G protein subunit st...

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Bibliographic Details
Main Authors: Rebeca Diez-Alarcia, Inés Ibarra-Lecue, Ángela Patricia López-Cardona, Javier Meana, Alfonso Gutierrez-Adán, Luis F Callado, Ekaitz Agirregoitia, Leyre Urigüen
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00415/full