Excitatory-inhibitory imbalance in Alzheimer's disease and therapeutic significance

The interplay between excitatory and inhibitory circuits underlies the brain's processes and their dysregulation has been linked to cognitive decline, psychiatric disorders and epilepsy. In patients with Alzheimer's disease (AD), an elevated occurrence of seizures has been observed in both...

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Bibliographic Details
Main Authors: Eva Vico Varela, Guillaume Etter, Sylvain Williams
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118307599