Anti-ICAM-1 antibody-modified nanostructured lipid carriers: a pulmonary vascular endothelium-targeted device for acute lung injury therapy

Anti-ICAM-1 antibody-modified nanostructured lipid carriers: a pulmonary vascular endothelium-targeted device for acute lung injury therapy

Abstract Background Acute lung injury (ALI) is a life-threatening clinical syndrome without effective treatment. Targeting delivery of glucocorticoid to lung shows potential efficacy for ALI based on their anti-inflammatory and anti-fibrotic properties, breaking through their clinical application li...

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Bibliographic Details
Main Authors: Shujuan Li, Li Chen, Guokang Wang, Lexing Xu, Shanshan Hou, Ziwei Chen, Xiaoling Xu, Xiaojuan Wang, Fuhe Liu, Yong-Zhong Du
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Journal of Nanobiotechnology
Subjects:
Acute lung injury
Pulmonary vascular endothelium-targeting
ICAM-1
Dexamethasone delivery
Surface charge
Online Access:http://link.springer.com/article/10.1186/s12951-018-0431-5

Internet

http://link.springer.com/article/10.1186/s12951-018-0431-5

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