Endothelial lipase concentrations are increased in metabolic syndrome and associated with coronary atherosclerosis.

Endothelial lipase (EL), a new member of the lipase family, has been shown to modulate high-density lipoprotein (HDL-C) metabolism and atherosclerosis in mouse models. We hypothesized that EL concentrations would be associated with decreased HDL-C and increased atherosclerosis in humans.Healthy indi...

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Bibliographic Details
Main Authors: Karen O Badellino, Megan L Wolfe, Muredach P Reilly, Daniel J Rader
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-02-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1316064?pdf=render