Effects of Quercetin on Mushroom Tyrosinase and B16-F10 Melanoma Cells

In searching for tyrosinase inhibitors from plants using L-3,4-dihydroxyphenylalanine (L-DOPA) as a substrate, quercetin was found to be partially oxidized to the corresponding o-quinone under catalysis by mushroom tyrosinase (EC 1.14.18.1). Simultaneously, L-DOPA was also oxidized to dopaquinone an...

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Bibliographic Details
Main Authors: Ken-ichi Nihei, Teruhiko Nitoda, Isao Kubo
Format: Article
Language:English
Published: MDPI AG 2007-05-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/12/5/1045/