Mechanochemical Formation of Racemic Praziquantel Hemihydrate with Improved Biopharmaceutical Properties
Praziquantel (PZQ) is the first-line drug used against schistosomiasis, one of the most common parasitic diseases in the world. A series of crystalline structures including two new polymorphs of the pure drug and a series of cocrystals of PZQ have been discovered and deposited in the Cambridge Struc...
Main Authors: | Debora Zanolla, Dritan Hasa, Mihails Arhangelskis, Gabriela Schneider-Rauber, Michele R. Chierotti, Jennifer Keiser, Dario Voinovich, William Jones, Beatrice Perissutti |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-03-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/12/3/289 |
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