Achillolide A Protects Astrocytes against Oxidative Stress by Reducing Intracellular Reactive Oxygen Species and Interfering with Cell Signaling

Achillolide A Protects Astrocytes against Oxidative Stress by Reducing Intracellular Reactive Oxygen Species and Interfering with Cell Signaling

Achillolide A is a natural sesquiterpene lactone that we have previously shown can inhibit microglial activation. In this study we present evidence for its beneficial effects on astrocytes under oxidative stress, a situation relevant to neurodegenerative diseases and brain injuries. Viability of bra...

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Bibliographic Details
Main Authors: Anat Elmann, Alona Telerman, Hilla Erlank, Rivka Ofir, Yoel Kashman, Elie Beit-Yannai
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Molecules
Subjects:
achillolide A
Achillea fragrantissima
astrocytes
oxidative stress
reactive oxygen species
mitogen-activated protein kinases (MAPK)
neurodegenerative diseases
Online Access:http://www.mdpi.com/1420-3049/21/3/301

Internet

http://www.mdpi.com/1420-3049/21/3/301

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