Mayaro Virus Replication Restriction and Induction of Muscular Inflammation in Mice Are Dependent on Age, Type-I Interferon Response, and Adaptive Immunity

Mayaro Virus Replication Restriction and Induction of Muscular Inflammation in Mice Are Dependent on Age, Type-I Interferon Response, and Adaptive Immunity

Mayaro virus (MAYV) is an emergent arbovirus first described in forest regions of the American continent, with recent and increasing notification of urban area circulation. Similar to Chikungunya (CHIKV) and other arthritogenic Alphavirus, MAYV-induced disease shows a high prevalence of persistent a...

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Bibliographic Details
Main Authors: Camila Menezes Figueiredo, Romulo Leão da Silva Neris, Daniel Gavino-Leopoldino, Mariana Oliveira Lopes da Silva, Juliana Silva Almeida, Julio Souza dos-Santos, Claudia Pinto Figueiredo, Maria Bellio, Marcelo Torres Bozza, Iranaia Assunção-Miranda
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Microbiology
Subjects:
mayaro virus
pathogenesis
replication restriction
type-I interferon response
adaptive immunity
muscle inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02246/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02246/full

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