Causal Effects of Genetically Determined Metabolites on Risk of Polycystic Ovary Syndrome: A Mendelian Randomization Study

Causal Effects of Genetically Determined Metabolites on Risk of Polycystic Ovary Syndrome: A Mendelian Randomization Study

Background: Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder that is influenced by both genetic and environmental factors. However, the etiology of PCOS remains unclear.Methods: We conducted a two-sample Mendelian randomization (MR) analysis to assess the causal effects of gene...

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Bibliographic Details
Main Authors: Shuliu Sun, Minjie Jiao, Chengcheng Han, Qian Zhang, Wenhao Shi, Juanzi Shi, Xiaojuan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Endocrinology
Subjects:
genetically determined metabolites
polycystic ovary syndrome
mendelian randomization
epiandrosterone sulfate
rs13222543
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00621/full

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https://www.frontiersin.org/article/10.3389/fendo.2020.00621/full

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