Synthesis and photodegradation studies of analogues of muscle relaxant 1,4-dihydropyridine compounds

Synthesis and photodegradation studies of analogues of muscle relaxant 1,4-dihydropyridine compounds

This paper describes the synthesis of 1,4-dihydropyridine compounds (DHPs) endowed with good muscle relaxant activity and stability to light. Six new condensed DHPs were synthesized by the microwave irradiation method. A long-chain ester moiety [2-(methacryloyloxy)ethyl] and various substituents on...

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Bibliographic Details
Main Authors: Gündüz Miyase Gözde, Ragno Gaetano, Şimşek Rahime, De Luca Michele, Şafak Cihat, Grande Fedora, El-Khouly Ahmed, İşli Fatma, Yildirim Şeniz, Öztürk Fincan Gökçe Sevim, Ioele Giuseppina
Format: Article
Language:English
Published: Sciendo 2017-09-01
Series:Acta Pharmaceutica
Subjects:
1,4-dihydropyridine compounds
muscle relaxant
drug design
structure activity relationship
photostability
mcr analysis
Online Access:https://doi.org/10.1515/acph-2017-0026

Internet

https://doi.org/10.1515/acph-2017-0026

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