Bax-inhibiting peptide attenuates bleomycin-induced lung injury in mice

Bax-inhibiting peptide attenuates bleomycin-induced lung injury in mice

Bax is a pro-apoptotic member of the Bcl-2 family of proteins, and plays a central role in mitochondria-dependent apoptosis. Several lines of evidence have implied that Bax is involved in both epithelial apoptosis and fibroblast proliferation in idiopathic pulmonary fibrosis; however, the mechanisms...

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Bibliographic Details
Main Authors: Kunihiro Suzuki, Toyoshi Yanagihara, Tetsuya Yokoyama, Takashige Maeyama, Saiko Ogata-Suetsugu, Masako Arimura-Omori, Hironori Mikumo, Naoki Hamada, Eiji Harada, Kazuyoshi Kuwano, Taishi Harada, Yoichi Nakanishi
Format: Article
Language:English
Published: The Company of Biologists 2017-12-01
Series:Biology Open
Subjects:
Bax
Lung injury
Apoptosis
Online Access:http://bio.biologists.org/content/6/12/1869

Internet

http://bio.biologists.org/content/6/12/1869

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