Is there a role for neuregulin 4 in human nonalcoholic fatty liver disease?

<h4>Background</h4>Neuregulin 4 (Nrg4), a novel adipokine enriched in brown adipose tissue has been observed to negatively regulate de novo hepatic lipogenesis and limit nonalcoholic fatty liver disease (NAFLD) progression to nonalcoholic steatohepatitis (NASH) in rodents. However, the r...

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Main Authors: Toon J I De Munck, Markus Boesch, Pauline Verhaegh, Ad A M Masclee, Daisy Jonkers, Jos F van Pelt, Johannie du Plessis, Hannelie Korf, Frederik Nevens, Ger H Koek, Schalk Van der Merwe, Jef Verbeek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0251822