Remodeling of the Nuclear Envelope and Lamina during Bovine Preimplantation Development and Its Functional Implications.

The present study demonstrates a major remodeling of the nuclear envelope and its underlying lamina during bovine preimplantation development. Up to the onset of major embryonic genome activation (MGA) at the 8-cell stage nuclei showed a non-uniform distribution of nuclear pore complexes (NPCs). NPC...

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Bibliographic Details
Main Authors: Jens Popken, Alexander Graf, Stefan Krebs, Helmut Blum, Volker J Schmid, Axel Strauss, Tuna Guengoer, Valeri Zakhartchenko, Eckhard Wolf, Thomas Cremer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4416817?pdf=render