RAGE Expression and ROS Generation in Neurons: Differentiation versus Damage

RAGE is a multiligand receptor able to bind advanced glycation end-products (AGEs), amphoterin, calgranulins, and amyloid-beta peptides, identified in many tissues and cells, including neurons. RAGE stimulation induces the generation of reactive oxygen species (ROS) mainly through the activity of NA...

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Bibliographic Details
Main Authors: S. Piras, A. L. Furfaro, C. Domenicotti, N. Traverso, U. M. Marinari, M. A. Pronzato, M. Nitti
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2016/9348651