Targeting NMDA receptors in stroke: new hope in neuroprotection

Abstract NMDA (N-methyl-d-aspartate) receptors (NMDARs) play a central role in excitotoxic neuronal death caused by ischemic stroke, but NMDAR channel blockers have failed to be translated into clinical stroke treatments. However, recent research on NMDAR-associated signaling complexes has identifie...

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Bibliographic Details
Main Authors: Qiu Jing Wu, Michael Tymianski
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Molecular Brain
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13041-018-0357-8