Dynamics of TCR repertoire and T cell function in COVID-19 convalescent individuals

Abstract SARS-CoV-2 outbreak has been declared by World Health Organization as a worldwide pandemic. However, there are many unknowns about the antigen-specific T-cell-mediated immune responses to SARS-CoV-2 infection. Here, we present both single-cell TCR-seq and RNA-seq to analyze the dynamics of...

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Bibliographic Details
Main Authors: Lingjie Luo, Wenhua Liang, Jianfeng Pang, Gang Xu, Yingying Chen, Xinrong Guo, Xin Wang, Yi Zhao, Yangdian Lai, Yang Liu, Bin Li, Bing Su, Shuye Zhang, Michal Baniyash, Lei Shen, Lei Chen, Yun Ling, Ying Wang, Qiming Liang, Hongzhou Lu, Zheng Zhang, Feng Wang
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-021-00321-x