Adoptive Immunotherapy for Hematological Malignancies Using T Cells Gene-Modified to Express Tumor Antigen-Specific Receptors

Adoptive Immunotherapy for Hematological Malignancies Using T Cells Gene-Modified to Express Tumor Antigen-Specific Receptors

Accumulating clinical evidence suggests that adoptive T-cell immunotherapy could be a promising option for control of cancer; evident examples include the graft-vs-leukemia effect mediated by donor lymphocyte infusion (DLI) and therapeutic infusion of ex vivo-expanded tumor-infiltrating lymphocytes...

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Bibliographic Details
Main Author: Hiroshi Fujiwara
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:Pharmaceuticals
Subjects:
adoptive immunotherapy
gene-modified T cell
T-cell receptor
chimeric antigen receptor
hematological malignancy
Online Access:http://www.mdpi.com/1424-8247/7/12/1049

Internet

http://www.mdpi.com/1424-8247/7/12/1049

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