Covalent α-synuclein dimers: chemico-physical and aggregation properties.

Covalent α-synuclein dimers: chemico-physical and aggregation properties.

The aggregation of α-synuclein into amyloid fibrils constitutes a key step in the onset of Parkinson's disease. Amyloid fibrils of α-synuclein are the major component of Lewy bodies, histological hallmarks of the disease. Little is known about the mechanism of aggregation of α-synuclein. During...

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Main Authors: Micaela Pivato, Giorgia De Franceschi, Laura Tosatto, Erica Frare, Dhruv Kumar, Daniel Aioanei, Marco Brucale, Isabella Tessari, Marco Bisaglia, Bruno Samori, Patrizia Polverino de Laureto, Luigi Bubacco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23272053/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23272053/pdf/?tool=EBI

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