Investigating the relationship between melatonin levels, melatonin system, microbiota composition and bipolar disorder psychopathology across the different phases of the disease

Abstract Background Bipolar disorder (BD) is characterized by recurrent episodes of depression and mania/hypomania alternating with intervals of well-being. The neurobiological underpinnings of BD are still veiled although there is evidence pointing to a malfunction of the circadian clock system tha...

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Bibliographic Details
Main Authors: Mirko Manchia, Alessio Squassina, Claudia Pisanu, Donatella Congiu, Mario Garzilli, Beatrice Guiso, Federico Suprani, Pasquale Paribello, Vittoria Pulcinelli, Maria Novella Iaselli, Federica Pinna, Flavia Valtorta, Bernardo Carpiniello, Stefano Comai
Format: Article
Language:English
Published: SpringerOpen 2019-12-01
Series:International Journal of Bipolar Disorders
Subjects:
Online Access:https://doi.org/10.1186/s40345-019-0163-y