New generation of DNA-based immunotherapy induces a potent immune response and increases the survival in different tumor models

Background Strategies to increase nucleic acid vaccine immunogenicity are needed to move towards clinical applications in oncology. In this study, we designed a new generation of DNA vaccines, encoding an engineered vesicular stomatitis virus glycoprotein as a carrier of foreign T cell tumor epitope...

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Bibliographic Details
Main Authors: Alessandra Lopes, Sophie Ligot, Gaëlle Vandermeulen, Chiara Bastiancich, Mathilde Bausart, Laure Lambricht, Kevin Vanvarenberg, Bernard Ucakar, Bernard Gallez
Format: Article
Language:English
Published: BMJ Publishing Group 2021-04-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/4/e001243.full