miR675 Accelerates Malignant Transformation of Mesenchymal Stem Cells by Blocking DNA Mismatch Repair

miR675 Accelerates Malignant Transformation of Mesenchymal Stem Cells by Blocking DNA Mismatch Repair

miR675 is highly expressed in several human tumor tissues and positively regulates cell progression. Herein, we demonstrate that miR675 promotes malignant transformation of human mesenchymal stem cells. Mechanistically, we reveal that miR675 enhances the expression of the polyubiquitin-binding prote...

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Bibliographic Details
Main Authors: Yanan Lu, Shuting Song, Xiaoxue Jiang, Qiuyu Meng, Chen Wang, Xiaonan Li, Yuxin Yang, Xiaoru Xin, Qidi Zheng, Liyan Wang, Hu Pu, Xin Gui, Tianming Li, Dongdong Lu
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253118303044

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http://www.sciencedirect.com/science/article/pii/S2162253118303044

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