Characterisation of the proximal airway squamous metaplasia induced by chronic tobacco smoke exposure in spontaneously hypertensive rats

<p>Abstract</p> <p>Background</p> <p>Continuous exposure to tobacco smoke (TS) is a key cause of chronic obstructive pulmonary disease (COPD), a complex multifactorial disease that is difficult to model in rodents. The spontaneously hypertensive (SH) rat exhibits severa...

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Bibliographic Details
Main Authors: Foster Martyn, Oreffo Victor, Pinnion Kate, Bolton Sarah J, Pinkerton Kent E
Format: Article
Language:English
Published: BMC 2009-11-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/10/1/118