Heterocellular spheroids of the neurovascular blood-brain barrier as a platform for personalized nanoneuromedicine

Summary: Nanoneuromedicine investigates nanotechnology to target the brain and treat neurological diseases. In this work, we biofabricated heterocellular spheroids comprising human brain microvascular endothelial cells, brain vascular pericytes and astrocytes combined with primary cortical neurons a...

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Bibliographic Details
Main Authors: Murali Kumarasamy, Alejandro Sosnik
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221001516