High-efficiency screening of monoclonal antibodies for membrane protein crystallography.

Determination of crystal structures of membrane proteins is often limited by difficulties obtaining crystals diffracting to high resolution. Co-crystallization with Fab fragments of monoclonal antibodies has been reported to improve diffraction of membrane proteins crystals. However, it is not simpl...

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Bibliographic Details
Main Authors: Hyun-Ho Lim, Yiling Fang, Carole Williams
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3169636?pdf=render