Functional heterogeneity in CD4+ T cell responses against a bacterial pathogen

Functional heterogeneity in CD4+ T cell responses against a bacterial pathogen

To investigate how CD4+ T cells function against a bacterial pathogen, we generated a Listeria monocytogenes-specific CD4+ T cell model. In this system, two TCRtg mouse lines, LLO56 and LLO118 recognize the same immunodominant epitope (LLO190-205) of Listeria monocytogenes and have identical in vitr...

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Bibliographic Details
Main Authors: Ashley eViehmann Milam, Paul M. Allen
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Immunology
Subjects:
Immunomodulation
Listeria monocytogenes
Thymocytes
Regulatory T Cell
CD5
CD4+ T cell
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00621/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00621/full

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