Effect of Cilnidipine on L- and T-type Calcium Currents in Guinea Pig Ventricle and Action Potential in Rabbit Sinoatrial Node

Cilnidipine, a dihydropyridine Ca2+ channel antagonist, is known to have inhibitory effects on both L- and N-type Ca2+ currents. In the present study, we examined the effect of cilnidipine on myocardial L- and T-type Ca2+ currents and sinoatrial node action potential configuration. In voltage clampe...

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Bibliographic Details
Main Authors: Kentaro Takeda, Reiko Yamagishi, Haruko Masumiya, Hikaru Tanaka, Koki Shigenobu
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319324223