Surface Adjustment of Reverse Phase Protein Arrays using Positive Control Spots
Reverse phase protein arrays (RPPA) measure the relative expression levels of a protein in many samples simultaneously. Observed signal from these arrays is a combination of true signal, additive background, and multiplicative spatial effects. Background subtraction alone is not sufficient to remove...
Main Authors: | E. Shannon Neeley, Keith A. Baggerly, Steven M. Kornblau |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2012-01-01
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Series: | Cancer Informatics |
Online Access: | https://doi.org/10.4137/CIN.S9055 |
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