P4.15 EFFECT OF RENIN ANGIOTENSIN SYSTEM BLOCKADE ON SOLUBLE KLOTHO, ARTERIAL STIFFNESS AND ALBUMINURIA IN PATIENTS WITH TYPE 2 DIABETES AND SYSTOLIC HYPERTENSION
Background: Soluble Klotho is an anti-ageing phosphaturic protein associated with cardiovascular and renal protection. In-vitro and in-vivo studies have demonstrated that rennin-angiotensin-system (RAS) blockade increases soluble Klotho levels. The effect of RAS blockers on soluble Klotho in patient...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Atlantis Press
2013-11-01
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Series: | Artery Research |
Online Access: | https://www.atlantis-press.com/article/125939011/view |