P4.15 EFFECT OF RENIN ANGIOTENSIN SYSTEM BLOCKADE ON SOLUBLE KLOTHO, ARTERIAL STIFFNESS AND ALBUMINURIA IN PATIENTS WITH TYPE 2 DIABETES AND SYSTOLIC HYPERTENSION

Background: Soluble Klotho is an anti-ageing phosphaturic protein associated with cardiovascular and renal protection. In-vitro and in-vivo studies have demonstrated that rennin-angiotensin-system (RAS) blockade increases soluble Klotho levels. The effect of RAS blockers on soluble Klotho in patient...

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Bibliographic Details
Main Authors: G. Maltese, G. Viberti, L. Gnudi, J. Karalliedde
Format: Article
Language:English
Published: Atlantis Press 2013-11-01
Series:Artery Research
Online Access:https://www.atlantis-press.com/article/125939011/view