Functional Characterization of Pembrolizumab Produced in Nicotiana benthamiana Using a Rapid Transient Expression System

Functional Characterization of Pembrolizumab Produced in Nicotiana benthamiana Using a Rapid Transient Expression System

The striking innovation and clinical success of immune checkpoint inhibitors (ICIs) have undoubtedly contributed to a breakthrough in cancer immunotherapy. Generally, ICIs produced in mammalian cells requires high investment, production costs, and involves time consuming procedures. Recently, the pl...

Full description

Bibliographic Details
Main Authors: Tanapati Phakham, Christine Joy I. Bulaon, Narach Khorattanakulchai, Balamurugan Shanmugaraj, Supranee Buranapraditkun, Chatikorn Boonkrai, Sarintip Sooksai, Nattiya Hirankarn, Yoshito Abe, Richard Strasser, Kaewta Rattanapisit, Waranyoo Phoolcharoen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Plant Science
Subjects:
Nicotiana benthamiana
molecular farming
transient expression
cancer immunotherapy
anti-PD-1 antibody
Pembrolizumab
Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2021.736299/full

Internet

https://www.frontiersin.org/articles/10.3389/fpls.2021.736299/full

Similar Items