Genome instability and aging: Cause or effect?
Genome instability, i.e., the tendency of the genome to undergo alterations in DNA information content through mutation, is considered a hallmark of aging. While mutations can be analyzed in clonal lineages, such as tumors, normal tissues have thus far not been amenable to mutation analysis except f...
Main Authors: | Jan Vijg, Cristina Montagna |
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Format: | Article |
Language: | English |
Published: |
KeAi Communications Co., Ltd.
2017-10-01
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Series: | Translational Medicine of Aging |
Online Access: | http://www.sciencedirect.com/science/article/pii/S246850111730010X |
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