Recurring Translocations in Barrett’s Esophageal Adenocarcinoma

Recurring Translocations in Barrett’s Esophageal Adenocarcinoma

Barrett’s esophagus (BE) is a premalignant metaplasia in patients with chronic gastroesophageal reflux disease (GERD). BE can progress to esophageal adenocarcinoma (EA) with less than 15% 5-year survival. Chromosomal aneuploidy, deletions, and duplication are early events in BE progression to EA, bu...

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Bibliographic Details
Main Authors: Manisha Bajpai, Anshuman Panda, Kristen Birudaraju, James Van Gurp, Amitabh Chak, Kiron M. Das, Parisa Javidian, Hana Aviv
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Genetics
Subjects:
Barrett’s epithelium
esophageal adenocarcinoma
chromosome translocation
fluorescence in situ hybridization
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.674741/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.674741/full

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