Pseudomonas aeruginosa Exolysin promotes bacterial growth in lungs, alveolar damage and bacterial dissemination

Abstract Exolysin (ExlA) is a recently-identified pore-forming toxin secreted by a subset of Pseudomonas aeruginosa strains identified worldwide and devoid of Type III secretion system (T3SS), a major virulence factor. Here, we characterized at the ultrastructural level the lesions caused by an ExlA...

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Bibliographic Details
Main Authors: Stéphanie Bouillot, Patrick Munro, Benoit Gallet, Emeline Reboud, François Cretin, Guillaume Golovkine, Guy Schoehn, Ina Attrée, Emmanuel Lemichez, Philippe Huber
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02349-0