The co-stimulatory effects of MyD88-dependent Toll-like receptor signaling on activation of murine γδ T cells.

γδ T cells express several different toll-like receptor (TLR)s. The role of MyD88- dependent TLR signaling in TCR activation of murine γδ T cells is incompletely defined. Here, we report that Pam3CSK4 (PAM, TLR2 agonist) and CL097 (TLR7 agonist), but not lipopolysaccharide (TLR4 agonist), increased...

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Bibliographic Details
Main Authors: Jinping Zhang, Jia Wang, Lan Pang, Guorui Xie, Thomas Welte, Vandana Saxena, Jason Wicker, Brian Mann, Lynn Soong, Alan Barrett, Willi Born, Rebecca O'Brien, Tian Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4169491?pdf=render