Troglitazone Inhibits Vascular Endothelial Growth Factor–Induced Angiogenic Signaling via Suppression of Reactive Oxygen Species Production and Extracellular Signal–Regulated Kinase Phosphorylation in Endothelial Cells

Troglitazone Inhibits Vascular Endothelial Growth Factor–Induced Angiogenic Signaling via Suppression of Reactive Oxygen Species Production and Extracellular Signal–Regulated Kinase Phosphorylation in Endothelial Cells

Thiazolidinediones, peroxisome proliferators-activated receptor gamma (PPARγ) ligands, have been recognized as a potential therapeutic agents for the treatment of pathological neovascularization. In the present study, we examined the molecular mechanism by which troglitazone (TROG), a PPARγ agonist,...

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Bibliographic Details
Main Authors:	Byung Chul Park, Dinesh Thapa, Jong Suk Lee, Su-Young Park, Jung-Ae Kim
Format:	Article
Language:	English
Published:	Elsevier 2009-01-01
Series:	Journal of Pharmacological Sciences
Online Access:	http://www.sciencedirect.com/science/article/pii/S1347861319311284

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