Synthetic cationic peptide IDR-1018 modulates human macrophage differentiation.

Macrophages play a critical role in the innate immune response. To respond in a rapid and efficient manner to challenges in the micro-environment, macrophages are able to differentiate towards classically (M1) or alternatively (M2) activated phenotypes. Synthetic, innate defense regulators (IDR) pep...

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Bibliographic Details
Main Authors: Olga M Pena, Nicole Afacan, Jelena Pistolic, Carol Chen, Laurence Madera, Reza Falsafi, Christopher D Fjell, Robert E W Hancock
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3538731?pdf=render