Mechanical hyperalgesia correlates with insulin deficiency in normoglycemic streptozotocin-treated rats
The triggers and pathogenesis of peripheral diabetic neuropathy are poorly understood, and this study evaluated the role of insulinopenia in nociceptive abnormalities in the streptozotocin (STZ) rat model of diabetes to test the hypothesis that, in addition to hyperglycemia, impairment of insulin si...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2006-11-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996106001768 |